The NFL Week 2 schedule continues the early season action on Thursday, September 17th 2026 when the Detroit Lions visit the Buffalo Bills at 8:15 p.m. ET on Prime Video. The week 2 NFL schedule also features a full Sunday slate and Monday Night Football to close the week.
NFL Week 2 Schedule
| Date | Logo | Opponent | Time | Tickets |
|---|---|---|---|---|
| Thursday | at Detroit Lions at Buffalo Bills | 8:15pm ETPrime Video | ||
| Sunday | at Carolina Panthers at Atlanta Falcons | 1:00pm ETFOX | ||
| Sunday | at Minnesota Vikings at Chicago Bears | 1:00pm ETFOX | ||
| Sunday | at Philadelphia Eagles at Tennessee Titans | 1:00pm ETFOX | ||
| Sunday | at Pittsburgh Steelers at New England Patriots | 1:00pm ETCBS | ||
| Sunday | at Green Bay Packers at NY Jets | 1:00pm ETFOX | ||
| Sunday | at Cleveland Browns at Tampa Bay Buccaneers | 1:00pm ETCBS | ||
| Sunday | at New Orleans Saints at Baltimore Ravens | 1:00pm ETCBS | ||
| Sunday | at Cincinnati Bengals at Houston Texans | 1:00pm ETCBS | ||
| Sunday | at Jacksonville Jaguars at Denver Broncos | 4:05pm ETCBS | ||
| Sunday | at Las Vegas Raiders at LA Chargers | 4:05pm ETCBS | ||
| Sunday | at Washington Commanders at Dallas Cowboys | 4:25pm ETFOX | ||
| Sunday | at Seattle Seahawks at Arizona Cardinals | 4:25pm ETFOX | ||
| Sunday | at Miami Dolphins at San Francisco 49ers | 4:25pm ETFOX | ||
| Sunday | at Indianapolis Colts at Kansas City Chiefs | 8:20pm ETNBC/Peacock | ||
| Monday | at NY Giants at LA Rams | 8:15pm ETESPN/ABC |
NFL Schedule Week 2 Breakdown
Thursday, September 17 2026
Detroit at Buffalo kicks off the week in prime time on Prime Video.
Sunday, September 20 2026
A full slate of 14 games includes eight 1:00 p.m. ET contests on FOX and CBS, two 4:05 p.m. ET games, three 4:25 p.m. ET games, and the Sunday Night Football matchup of Indianapolis at Kansas City on NBC/Peacock.
Monday, September 21 2026
NY Giants at LA Rams closes the week 2 NFL schedule on ESPN/ABC at 8:15 p.m. ET.
NFL Schedule Week 2: Early Tests and Rivalries
Week 2 of the 2026 NFL season brings a mix of divisional battles and interconference tests that will start to separate early contenders from the pack. After the unique Wednesday opener in Week 1, the schedule returns to a more familiar rhythm with Thursday Night Football, a busy Sunday, and Monday Night Football.
The Lions and Bills open the week in a high-profile Thursday night matchup that pits two talented offenses against each other. On Sunday, several NFC North, NFC South, and AFC games offer early looks at how teams are adjusting after the first week of play. The Sunday Night Football game between Indianapolis and Kansas City and the Monday night clash between the Giants and Rams give fans two more primetime windows to watch.
Key Games to Watch in NFL Schedule Week 2
- Detroit at Buffalo (Thu) — Early-season test between two strong teams on Prime Video.
- Green Bay at NY Jets (Sun) — Packers look to build momentum on the road.
- Miami at San Francisco (Sun) — Interconference clash with playoff implications already forming.
- Indianapolis at Kansas City (Sun Night) — Colts face the defending champions in prime time.
- NY Giants at LA Rams (Mon Night) — NFC matchup to close the week.
Where to Watch NFL Schedule Week 2
Confirmed networks for the NFL Week 2 schedule:
- Prime Video (Thursday Night Football)
- FOX & CBS (Sunday afternoon)
- NBC/Peacock (Sunday Night Football)
- ESPN/ABC (Monday Night Football)
The NFL Week 2 schedule continues to build early-season storylines with a balanced mix of afternoon games and high-profile primetime matchups.
FAQ
When does the NFL Week 2 schedule start?
The NFL Week 2 schedule begins on Thursday, September 17 with Detroit at Buffalo at 8:15 p.m. ET on Prime Video.
What is the Sunday Night Football game in Week 2 NFL?
Indianapolis visits Kansas City on Sunday, September 20 at 8:20 p.m. ET on NBC/Peacock.
What is the Monday Night Football game in the Week 2 NFL schedule?
The NY Giants travel to face the LA Rams on Monday, September 21 at 8:15 p.m. ET on ESPN/ABC.
How many games are in the NFL Week 2 schedule?
The NFL Week 2 schedule features 16 games across Thursday, Sunday, and Monday.2